fig2

Figure 2. Crosstalk among adipose tissue, liver, and skeletal muscle. The figure shows the main adipokines, hepatokines, and myokines interplaying with target organs under insulin resistance condition. ↓In red represents a decrease and ↑in green represents an increase in action. FFA: Free fatty acids; TNF-α: tumor necrosis factor alpha; IL-6: interleukin-6; LECT2: leukocyte cell-derived chemotaxin 2; SelP: selenoprotein P; IGF-1: insulin growth factor; 11β-HSD1: 11β-hydroxysteroid dehydrogenase type 1; 11β-HSD2: 11β-hydroxysteroid dehydrogenase type 2.