fig1

Figure 1. The proposed interplay between insulin resistance and NAFLD/MAFLD and subsequent development of diabetes, chronic kidney disease, and cardiac disease. NAFLD: Nonalcoholic fatty liver disease; MAFLD: metabolic associated fatty liver disease; ROS: Reactive oxygen species; BUN: blood urea nitrogen; RAAS: renin-angiotensin-aldosterone system; GGT: gamma-glutamyl transferase.